Recirculated normal platelets adhere to surfaces coated with plasma from patients with immune thrombocytopenia
نویسندگان
چکیده
منابع مشابه
PLATELETS AND THROMBOPOIESIS Defective regulatory B-cell compartment in patients with immune thrombocytopenia
B lymphocytes producing antiplatelet autoantibodies play a major role in autoimmune thrombocytopenia (ITP). However, certain B cells, including the human CD19 CD24hiCD38hi subpopulation, possess regulatory functions mediated partly by IL-10. In a cohort of chronic ITP patients with low platelet counts who consisted of patients off treatment, we found a lower frequency of CD19 CD24hiCD38hi in th...
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چکیده ندارد.
Immune Thrombocytopenia Associated with Hepatitis A Infection in Children
Hepatitis A infection is usually a self–limited disease during childhood. Autoimmune manifestations are rarely reported among patients with HA infection. We describe a previously healthy 6-yr-old male with acute hepatitis A who developed immune thrombocytopenia.
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Variant von Willebrand disease designated as type I New York or type Malmo is characterized by enhanced ristocetin-induced platelet agglutination with normal von Willebrand factor multimeric distribution in plasma. We have studied four such patients belonging to three unrelated families and found in all of them a unique cytosine-to-thymine transition changing the codon for Pro" (CCG) to Leu (CI...
متن کاملThe amount of platelet-bound albumin parallels the amount of IgG on washed platelets from patients with immune thrombocytopenia.
The biologic relevance of the increased platelet-associated IgG (PAIgG) on platelets from patients with idiopathic thrombocytopenic purpura (ITP) is unclear. Platelets from ITP patients are often larger than normal, and it is possible that the increased IgG is not specific but passively related to platelet size. The measurement of platelet-bound albumin could provide information concerning the ...
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ژورنال
عنوان ژورنال: Blood Coagulation & Fibrinolysis
سال: 1997
ISSN: 0957-5235
DOI: 10.1097/00001721-199701000-00010